VITALdb : A gateway to viroinformatics knowledgebases, tools and algorithms

The recent pandemics of viral diseases, COVID-19/mpox (humans) and lumpy skin disease (cattle), have kept us glued to viral research. These outbreaks have exposed the urgency for early diagnosis of viral infections, vaccine development, and discovery of novel antiviral drugs and therapeutics. To support this, VITALdb (Viroinformatics tools and algorithms database) is a one-stop platform for ~360 viroinformatics knowledgebases encompassing all major viruses [SARS-Cov-2, Influenza virus, Human Immunodeficiency Virus (HIV), Papillomavirus, Herpes Simplex Virus (HSV), Hepatitis virus, Dengue virus, Ebola virus, Zika virus etc.] and several diverse applications [structural and functional annotation, antiviral peptides development, subspecies characterization, recognition of viral recombination, inhibitors identification, phylogenetic analysis, virus-host prediction, viral metagenomics, detection of mutation(s), primer designing etc]. VITALdb will not only facilitate further developments in the realm of viroinformatics but also provide a tremendous fillip to translate fundamental knowledge into applied research.

References:
  1. Sharma D, Priyadarshini P and Vrati S (2015) Unravelling the web of viroinformatics: computational tools and databases in virus research. J Virol, 89, 1489-1501. [DOI]
  2. Koul M, Kaushik S, Singh K and Sharma D (2025) VITALdb: to select the best viroinformatics tools for a desired virus or application. Brief Bioinform, 26, bbaf084.[DOI]